
An article on Polygonum cuspidatum, a commercial source of resveratrol, came out in the Journal of Clinical Endocrinology and Metabolism, June 9, 2010 which shows that resveratrol has the potential to delay aging. This study was done in animal models and in vitro (laboratory test). In general the observations were the reduction of oxidative stress which translates into an anti-oxidant power and also the inflammatory stress. These are the major mechanisms for longevity and stress, and imply that resveratrol can be help delay aging and biological stress. [Journal of Clinical Endocrinology & Metabolism , doi:10.1210/jc.2010-0482]
To correlate this with the study at Harvad University by Dr. David Sinclair, he reported that grapes naturally produce resveratrol which could fight age related diseases by studying genetic materials and reduce the pathologic effects of high fat diet by mimicking caloric restriction. [Cell 97 (5): 609–20.doi:10.1016/S0092-8674(00)80772-2. PMID 10367890.] This apparently has something to do with the French paradox, wherein French people’s consumption of red wine could explain why France has low rates of cardiovascular disease despite the high consumption of fat relative to the United States.
The Japanese knotweed, Polygonum cuspidatum has the highest amount of resveratrol followed by grapes, and among the varieties of grapes, the muscadine grapes are the next best source. Resveratrol can also be found in other red or purple grapes, peanuts, cranberry, raspberry, and blueberries.













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